Increased tryptase in children with allergic reactions to hazelnut
نویسندگان
چکیده
Background Mast cells are activated during allergic reactions, releasing inflammatory mediators that include tryptase. This process leads to the symptoms of an allergic reaction. A transient increase in the total level of serum tryptase indicates mast cell activation, e.g. an anaphylactic reaction. This may help to confirm and assess the extent of a systemic reaction. In the current study, the total level of serum tryptase was measured at different time points; before, during and after double-blind placebo-controlled food challenge (DBPCFC) with hazelnut in 40 suspected hazelnut allergic children aged 6-18 years. Total serum tryptase was measured with ImmunoCAP Tryptase, Thermo Fisher Scientific, Uppsala, Sweden.
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